WebJul 1, 2024 · Cryptotanshinone is a diterpene quinone derived from the roots of Salvia miltiorrhiza Bunge. An increasing number of studies have demonstrated that … WebTanshinone IIA (150) is the most abundant lipophilic compound in Danshen. Tanshinone I (144), cryptotanshinone (110 ), and 15,16-dihydrotanshinone I ( 51) are also the main constituents of the plant. Thus, the biological studies have prominently focused on these relatively abundant compounds.
Identification of the antibacterial mechanism of …
WebFeb 8, 2024 · In conclusion, while STAT3 regulates matrix metalloproteinase-9 and connective tissue growth factor expression in diabetic rats with cardiac fibrosis, cryptotanshinone inhibited fibrosis to improve cardiac function by suppressing the STAT3 pathway. Cryptotanshinone is suitable as an alternative remedy for therapy of cardiac … WebNov 5, 2024 · Cryptotanshinone (CT) is an extract from the traditional Chinese medicine Salvia miltiorrhiza, which inhibits the growth of methicillin-resistant Staphylococcus … gwyneth paltrow trial day 7
Cryptotanshinone Inhibits STAT3 Signaling to ... - Wiley Online Library
WebCryptotanshinone Cryptotanshinone (CTS), extracted from the root of Salvia miltiorrhiza Bunge, has a prominent anticancer action through inhibiting activation of STAT3 (Lu et al., 2024). From: New Look to Phytomedicine, 2024 View all Topics Add to Mendeley Download as PDF About this page Pharmacological Advances in Natural Product Drug Discovery WebModern pharmacological studies have shown that Cryptotanshinone has the effects of antibacterial, anti-inflammatory, antiobesity, and antidiabetic activity [ 12, 13] and has been prescribed for several diseases, including coronary heart disease (CHD), angina pectoris, and myocardial damage. WebSep 2, 2024 · Cryptotanshinone reduced the level of Aβ monomers and highly toxic oligomers in C. elegans while inhibiting the abnormal aggregation of polyglutamine protein. In addition, CTS upregulated the expression of hsp-16.2 and downregulated the expression of ace-2. These results suggested that CTS could alleviate oxidative stress and reduce the … gwyneth paltrow trial glasses