Siglec 10 antibody
Like most but not all other Siglecs, Siglec-10 bears an ITIM (Immunoreceptor tyrosine-based inhibitory motif) within its cytoplasmic domain. Siglec-10 is a ligand for CD52, the target of the therapeutic monoclonal antibody Alemtuzumab. It is also reported to bind to Vascular adhesion protein 1 (VAP-1) and to … See more Sialic acid-binding Ig-like lectin 10 is a protein that in humans is encoded by the SIGLEC10 gene. Siglec-G is often referred to as the murine paralog of human Siglec-10 See more SIGLECs are members of the immunoglobulin superfamily that are expressed on the cell surface. Most SIGLECs have 1 or more cytoplasmic immune receptor … See more • Li N, Zhang W, Wan T, et al. (2001). "Cloning and characterization of Siglec-10, a novel sialic acid binding member of the Ig superfamily, from human dendritic cells". J. Biol. Chem. 276 (30): 28106–12. doi:10.1074/jbc.M100467200. PMID 11358961. See more WebPRO940 antibody, SIGLEC-10 antibody, SLG2 antibody, Siglecg antibody, SIGLEC10 antibody, slg2 antibody, pro940 antibody, siglec-10 antibody, sialic acid binding Ig like …
Siglec 10 antibody
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WebIn one embodiment, an anti-Siglec-9 antibody has a KD of about 1×10 −7 M to about 1×10 −10 M, about 1×10 −8 M to about 1×10 −10 M, or about 1×10 −9 M to about 1×10 −11 M, … WebSpecificity. Clone 5G6 specifically recognizes human Siglec-10 (Sialic acid-binding Ig-like lectin 10), a putative adhesion molecule and member of the Ig superfamily, expressed by …
WebSiglec-G is the apparent ortholog of human Siglec-10 (4). The human Siglec-10 cDNA encodes a 697 amino acid (aa) precursor that includes a 16 aa signal sequence, a 534 aa extracellular domain (ECD), a 21 aa transmembrane segment, and a 126 aa cytoplasmic domain. The ECD contains one Ig-like V‑type domain and four Ig-like C2-type domains ... WebJul 4, 2014 · Siglec-10 (human homolog of mouse Siglec-G) was detected on all B cells and also subsets of human leukocytes including eosinophils, monocytes and a minor …
WebHigh-quality Siglec-10 proteins from ACROBiosystems. Various species and tags of Siglec-10 proteins. Minimal Batch-to-Batch Variation. Bulks in stock. Login Register. Bulk order. … WebSIGLEC10 (MGC126774, PRO940, SIGLEC-10, SLG2) protein expression summary. We use cookies to enhance the usability of our website. If you continue, we'll assume that you are …
WebFlow cytometric analysis of Siglec-10 expression on human peripheral blood lymphocytes. Human whole blood was stained with Alexa Fluor® 488 Mouse Anti-Human CD19 antibody (Cat. No. 555412) and either BD Horizon™ BV421 Mouse IgG1, κ Isotype Control (Cat. No. 562438; Left Plot) or BD Horizon BV421 Mouse Anti-Human Siglec-10 antibody (Cat. No. …
WebJul 31, 2024 · The blockade of Siglec-10 using monoclonal antibodies augmented the phagocytic ability of macrophages, thereby confirming a role for Siglec-10 in inhibiting … mothball historyWebNov 10, 2024 · AK007 is a humanized Siglec-10 antagonist antibody designed to block Siglec-10 interaction with all known ligands (CD24, CD52, and VAP-1). By targeting Siglec … mothball hangerWebMay 20, 2024 · Indeed, B-cell activation by antibodies to the B-cell receptor IgD is dramatically suppressed by conjugation of anti-IgD with high affinity ligands of a B-cell … mini portable waffle makerWebMonoclonal Anti-Siglec-10 antibody produced in mouse. clone 1D11, purified immunoglobulin, buffered aqueous solution. View Price and Availability. Sigma-Aldrich. … mini portable projector + shopifyWebAbcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that … mini portable usb wired desktop speakerWebWe offer Siglec-10 Antibodies for use in common research applications: Blockade of Receptor-ligand Interaction, ELISA, Flow Cytometry, Immunohistochemistry, … mini portable houses floor plansWebHigh-quality Siglec-10 proteins from ACROBiosystems. Various species and tags of Siglec-10 proteins. Minimal Batch-to-Batch Variation. Bulks in stock. Login Register. Bulk order. Clear ... Antibodies Anti-idiotypic antibody Anti-FMC63 mAb … mothball holder outdoor